Dicarboxylic acids and derivatives
![Medchemexpress LLC 3-cyclopropyl-1-[[4-[6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-5-fluoropyridin-2-yl]phenyl]methyl]imi | 2250025-91-1 | Not found | 99.4% | 508.99 | C23H25FN4O4S·HCl | 25MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236923.png-250.jpg)
Medchemexpress LLC 3-cyclopropyl-1-[[4-[6-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]-5-fluoropyridin-2-yl]phenyl]methyl]imi | 2250025-91-1 | Not found | 99.4% | 508.99 | C23H25FN4O4S·HCl | 25MG
LEI-101 hydrochloride is a potent, selective, orally bioavailable cannabinoid CB2 receptor agonist supplied for research use. It demonstrates strong functional activity at human CB2 receptors with substantially lower affinity for CB1 and minimal hERG binding, suitable for in vitro and in vivo pharmacology studies.
- Purity 99.4%.
- Reported activity pEC50 = 8 for human CB2.
- Approximately 100-fold selectivity for CB2 over CB1.
- Low hERG interaction (pKi < 4).
- Soluble in DMSO; available as dry powder and 10 mM solution in DMSO.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Ji-101 | 900573-88-8 | MFCD26142530 | 99.8% | 466.33 | C22H20BrN5O2 | 10 MG
JI-101 is an orally available multi-kinase inhibitor that targets VEGFR2, PDGFRβ, and EphB4 and has demonstrated potent anti-cancer activity. It is provided as a white to off-white solid powder for research use and is commonly supplied in a 10 mg pack.
- Orally available multi-kinase inhibitor active against VEGFR2, PDGFRβ, and EphB4.
- High purity (99.78%).
- Molecular formula C22H20BrN5O2; molecular weight 466.33 g/mol.
- White to off-white solid, soluble in DMSO at ≥ 100 mg/mL.
- Intended for research use only; not for human administration.
TARGETMOL CHEMICALS INC PKUMDL-LC-101-D04 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4) a regulator of iron death. GPX4 activity was increased to 150% of control levels when used at a concentration of 20 uM in a cell-free assay and at a concentration of 61 uM in wild-type but not Gpx4-/- mouse embryonic fibroblast (MEF) extracts.PKUMDL-LC-101-D04 (200 uM) reduced cholesterol peroxide-induced MEF death. purity: 98%
Selleck Chemical LLC CUDC-101 S1194-1g
CUDC-101 is a potent multi-targeted inhibitor against HDAC EGFR and HER2 with IC50 of 4 4 nM 2 4 nM and 15 7 nM and inhibits class I/II HDACs but not class III Sir-type HDACs Phase 1
Medchemexpress LLC Lauroyl-L-carnitine chloride | 6919-91-1 | MFCD00274131 | 98.1% | C19H38ClNO4 | 10MG
Lauroyl-L-carnitine chloride is an orally active absorption enhancer used in research to improve the oral bioavailability of peptide compounds. Supplied as a white to off-white solid with high purity, it is applied in formulation and permeability studies to assess and enhance intestinal uptake of peptide drugs.
- Orally active absorption enhancer for peptide compounds.
- Reported to improve oral bioavailability of peptides.
- White to off-white solid suitable for formulation research.
- High purity (~98.1%) as supplied.
- Supports studies of intestinal permeability and delivery.
- Store sealed at 4°C; in solvent, -80°C (6 months) or -20°C (1 month).
Selleck Chemical LLC (R)-(-)-Gossypol (AT-101) acetic acid S2812-50mg
(R)-(-)-Gossypol (AT-101) acetic acid the R-(-) enantiomer of Gossypol acetic acid binds with Bcl-2 Bcl-xL and Mcl-1 with Ki of 0 32 M 0 48 M and 0 18 M in cell-free assays does not inhibit BIR3 domain and BID AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy Phase 2
Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 g·mol⁻1 | C29H58NO8P | 50 MG
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a phosphatidylethanolamine lipid with lauric (12:0) acyl chains. It is commonly used as a lipid component for preparing liposomes and for studies of membrane composition in biochemical and biophysical research.
- High purity suitable for research applications.
- Useful for liposome synthesis and membrane composition studies.
- Available in multiple small pack sizes for laboratory use.
- Contains lauric (12:0) acyl chains for defined lipid composition.
- Molecular weight 579.75 g·mol⁻1 and formula C29H58NO8P for accurate formulation.
Medchemexpress LLC 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine | 59752-57-7 | MFCD00042828 | 98.0% | 579.75 | C29H58NO8P | 25 MG
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a phosphatidylethanolamine lipid bearing lauric acid (12:0) acyl chains. It is commonly used as a lipid component in the preparation of liposomes and other lipid-based formulations for research use only. The material is supplied as a white to off-white solid with high purity and specified storage conditions.
- Phosphatidylethanolamine derivative with C12:0 acyl chains.
- Suitable as a lipid component for liposome synthesis.
- High purity for research applications.
- Available in small laboratory quantities (e.g., 25 mg, 50 mg, 100 mg).
- White to off-white solid; store powder at -20°C.
![Medchemexpress LLC 1-propanaminium, 3-carboxy-N,N,N-tri(methyl-d3)-2-[(1-oxododecyl)oxy]-, chloride (1:1), (2R)- | 2245711-25-3 | 98.0% | C19H29D9ClNO4 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260025.png-250.jpg)
Medchemexpress LLC 1-propanaminium, 3-carboxy-N,N,N-tri(methyl-d3)-2-[(1-oxododecyl)oxy]-, chloride (1:1), (2R)- | 2245711-25-3 | 98.0% | C19H29D9ClNO4 | 10MG
Lauroyl-L-carnitine-d9 chloride is the deuterium-labeled (d9) chloride salt of lauroyl-L-carnitine supplied as an isotope-labeled reference standard for analytical and research use. It is intended for use as an internal standard or tracer in mass spectrometry, quantitative assays, and metabolic or pharmacokinetic studies, providing a labeled analog of the unlabeled compound.
- Deuterium-labeled (d9) isotope suitable for use as an internal standard in mass spectrometry.
- Chloride salt form to match common analytical reference materials.
- High purity (98.0%) for reliable analytical performance.
- Provided in small, reference quantities tailored for analytical workflows.
- Stable when stored sealed under refrigerated conditions (≈2-8°C).
Medchemexpress LLC ULK-101 1mg | 2443816-45-1 | 1 MG
ULK-101 is a potent, selective small-molecule inhibitor of ULK1 (unc-51-like autophagy activating kinase 1) that suppresses autophagy and can sensitize cancer cells to nutrient stress. It is supplied as a research-grade solid for in vitro studies.
- Potent ULK1 inhibition; reported low-nanomolar IC50 for ULK1, ULK2 ~30 nM
- Suppresses autophagy and sensitizes cancer cells to nutrient stress
- Molecular formula C22H16F4N4OS and molecular weight ~460.4 g/mol
- Provided as a 1 mg quantity suitable for assay development and biochemical studies
TARGETMOL CHEMICALS INC GLYH-101 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM. purity: 98%
Medchemexpress LLC UK-101 | 1000313-40-5 | 99.6% | 484.74 g/mol | C25H48N2O5Si | 25 MG
UK-101 is a potent, selective immunoproteasome β1i (LMP2) inhibitor intended for research use. It has a reported IC50 of 104 nM against LMP2, with significant selectivity over the constitutive β1c and β5 proteasome subunits. UK-101 is used in cell-based studies to induce apoptosis and to investigate immunoproteasome function and cancer-related pathways. Supplied as a powder with recommended storage conditions to preserve stability.
- Potent LMP2 (β1i) inhibitor with IC50 ≈ 104 nM.
- Selective over proteasome β1c and β5 subunits.
- Induces apoptosis in cell-based assays.
- High purity suitable for biochemical and cellular studies.
- Supplied as powder with recommended storage for long-term stability.